Welcome to the DDG

The DDG provides a complete pipeline of services for initial target analysis and hit finding to lead optimisation and library design. We specialise in novel and 'difficult' targets including GPCRs and protein-protein interactions.

focussed library We integrate with and complement your existing projects at any point within the design process.

A list of the main protocols/services from the DDG is given on the right.

The DDG scientists come from both industry and academia and have a wide range of experience in all facets of early drug design, protein modelling, sequence analysis, algorithm/programming skills, database searching and integration, web interface development, graphic design and scientific data analysis.

We have a flexible approach to working with our clients and are able to provide anything from a single day's consultancy service to full project management.

If any of these services are of interest to you please contact us at:

info [at] drugdesigngroup.com
Molecular Modelling

  • Homology modelling
  • Protein electrostatics
  • Site analysis
  • GPCR modelling
  • Molecular Dynamics


  • Sequence analysis
  • Database searching
  • Genome analysis (SNPs)
  • Pairwise and multiple alignments
  • Data mining
  • Pattern searching
  • Clustering


  • Database filtering
  • Target focussed screening
  • Property calculations
  • QSAR
  • ADMET profiling

Drug Design

  • Pharmacophore mapping
  • Ligand docking
  • Virtual screening
  • Fragment screening
  • De novo design
  • Library design